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Journal of Trauma and Injury 2013;26(3):63-73.
Current Concept and Future of the Management of Spinal Cord Injury: A Systematic Review
Il Choi, Jin Gyeong Ha, Sang Ryong Jeon
Department of Neurological Surgery, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea. srjeon@amc.seoul.kr
척수손상 치료 약제의 현재와 미래: 체계적 고찰
최 일, 하진경, 전상용
울산대학교 의과대학 서울아산병원 신경외과학교실
Received: 6 February 2013   • Revised: 19 April 2013   • Accepted: 1 July 2013
Abstract
Spinal cord injury (SCI) is a serious condition associated with social and familial burden, as well as significant neurologic deficit. Despite the many advances in the treatment of spinal cord injury, a fundamental treatment for neurologic functional recovery has not yet been developed. In this article, we review two directions of development for spinal cord injury treatment: neuroprotective pharmacological agents and axon-regenerating cell therapy. We expect developments in these two to lead to improve functional recovery in patients with spinal cord injuries and to reduce burdens on society, as well as the patients' families.
Key Words: Cell therapy; Pharmacologic therapy; Spinal cord injuries; Stem cell
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