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Kyu Hyouck Kyoung 1 Article
The Timing of Femur Fracture Fixation is an Important Factor for Prolonged Mechanical Ventilation
Hyung Chul Choi, Kwang Hwan Jung, Kyu Hyouck Kyoung, Seong Ho Choi
J Trauma Inj. 2019;32(4):220-225.   Published online December 30, 2019
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AbstractAbstract PDF

Mechanical ventilation (MV) is an essential life-saving modality for severely injured patients. However, the long-term use of MV is a major risk factor for late mortality. The surgical correction of long bone fractures plays a critical role not only in improving functional outcomes, but also in reducing physiological derangements, including MV duration. This study investigated the factors affecting prolonged MV (PMV) in severely injured patients with femur fractures.


We retrospectively evaluated all severely injured patients (injury severity score >15) with femur fractures who were taken to the emergency department within 12 hours of the causative accidents between January 2016 and December 2018. PMV was defined as MV lasting for ≥7 days. We analyzed the factors affecting PMV.


In total, 35 patients were enrolled and 21 (33.3%) were included in the PMV group. The PMV group required more red blood cell (RBC) transfusions within 7 days RBC (7dRBC) (12.8 vs. 6.8 units; p=0.03) and the time to femur fracture fixation (TFFF) was longer (7.9 vs. 2.7 days; p=0.018). The area under the curve (AUC) for TFFF was 0.740 (95% confidence interval [CI]: 0.572–0.908; p=0.018) and the AUC for 7dRBC was 0.718 (95% CI: 0.546–0.889; p=0.031).


This study indicates that TFFF is an independent risk factor for PMV. Early fixation of femur fractures might prevent PMV and its associated complications.



Citations to this article as recorded by  
  • Management of Traumatic Femur Fractures: A Focus on the Time to Intramedullary Nailing and Clinical Outcomes
    Syed Imran Ghouri, Fuad Mustafa, Ahad Kanbar, Hisham Al Jogol, Adam Shunni, Ammar Almadani, Nuri Abdurraheim, Atirek Pratap Goel, Husham Abdelrahman, Elhadi Babikir, Ahmed F. Ramzee, Khalid Ahmed, Mutaz Alhardallo, Mohammad Asim, Hassan Al-Thani, Ayman El
    Diagnostics.2023; 13(6): 1147.     CrossRef

J Trauma Inj : Journal of Trauma and Injury