- Predictors of massive transfusion protocols activation in patients with trauma in Korea: a systematic review
-
Dongmin Seo, Inhae Heo, Juhong Park, Junsik Kwon, Hye-min Sohn, Kyoungwon Jung
-
J Trauma Inj. 2024;37(2):97-105. Published online June 14, 2024
-
DOI: https://doi.org/10.20408/jti.2024.0015
-
-
2,853
View
-
128
Download
-
1
Citations
-
Abstract
PDF Supplementary Material
- Purpose
Massive transfusion protocols (MTPs) implementation improves clinical outcomes of the patient’s resuscitation with hemorrhagic trauma. Various predictive scoring system have been used and studied worldwide to improve clinical decision. However, such research has not yet been studied in Korea. This systematic review aimed to assess the predictors of MTPs activation in patients with trauma in Korea.
Methods The PubMed, Embase, Cochrane Library, Research Information Sharing Service databases, KoreaMed, and KMbase were searched from November 2022. All studies conducted in Korea that utilized predictors of MTPs activation in adult patients with trauma were included.
Results Ten articles were eligible for analysis, and the predictors were assessed. Clinical assessments such as systolic and diastolic blood pressure, shock index (SI), prehospital modified SI, modified early warning system (MEWS) and reverse SI multiplied by the Glasgow Coma Scale (rSIG) were used. Laboratory values such as lactate level, fibrinogen degradation product/fibrinogen ratio, and rotational thromboelastometry (ROTEM) were used. Imaging examinations such as pelvic bleeding score were used as predictors of MTPs activation.
Conclusions Our systematic review identified predictors of MTPs activation in patients with trauma in Korea; predictions were performed using tools that requires clinical assessments, laboratory values or imaging examinations only. Among them, ROTEM, rSIG, MEWS, SI, and lactate level showed good effects for predictions of MTPs activation. The application of predictors for MTP’s activation should be individualized based on hospital resource and skill set, also should be performed as a clinical decision supporting tools.
-
Summary
-
Citations
Citations to this article as recorded by 
- A Case Study on Simulation Training for Operational Improvements in the Massive Transfusion Protocol
Sooin Choi, Jongbin Wee, Haeri Jung, Young Soon Cho The Korean Journal of Blood Transfusion.2024; 35(2): 113. CrossRef
- Clinical Practice Guideline for the Treatment of Traumatic Shock Patients from the Korean Society of Traumatology
-
Pil Young Jung, Byungchul Yu, Chan-Yong Park, Sung Wook Chang, O Hyun Kim, Maru Kim, Junsik Kwon, Gil Jae Lee
-
J Trauma Inj. 2020;33(1):1-12. Published online March 30, 2020
-
DOI: https://doi.org/10.20408/jti.2020.015
-
-
25,499
View
-
1,332
Download
-
4
Citations
-
Abstract
PDF
- Purpose
Despite recent developments in the management of trauma patients in South Korea, a standardized system and guideline for trauma treatment are absent.
Methods
Five guidelines were assessed using the Appraisal of Guidelines for Research and Evaluation II instrument.
Results
Restrictive volume replacement must be used for patients experiencing shock from trauma until hemostasis is achieved (1B). The target systolic pressure for fluid resuscitation should be 80–90 mmHg in hypovolemic shock patients (1C). For patients with head trauma, the target pressure for fluid resuscitation should be 100–110 mmHg (2C). Isotonic crystalloid fluid is recommended for initially treating traumatic hypovolemic shock patients (1A). Hypothermia should be prevented in patients with severe trauma, and if hypothermia occurs, the body temperature should be increased without delay (1B). Acidemia must be corrected with an appropriate means of treatment for hypovolemic trauma patients (1B). When a large amount of transfusion is required for trauma patients in hypovolemic shock, a massive transfusion protocol (MTP) should be used (1B). The decision to implement MTP should be made based on hemodynamic status and initial responses to fluid resuscitation, not only the patient’s initial condition (1B). The ratio of plasma to red blood cell concentration should be at least 1:2 for trauma patients requiring massive transfusion (1B). When a trauma patient is in life-threatening hypovolemic shock, vasopressors can be administered in addition to fluids and blood products (1B). Early administration of tranexamic acid is recommended in trauma patients who are actively bleeding or at high risk of hemorrhage (1B). For hypovolemic patients with coagulopathy non-responsive to primary therapy, the use of fibrinogen concentrate, cryoprecipitate, or recombinant factor VIIa can be considered (2C).
Conclusions
This research presents Korea's first clinical practice guideline for patients with traumatic shock. This guideline will be revised with updated research every 5 years.
-
Summary
-
Citations
Citations to this article as recorded by 
- External validation of an artificial intelligence model using clinical variables, including ICD-10 codes, for predicting in-hospital mortality among trauma patients: a multicenter retrospective cohort study
Seungseok Lee, Do Wan Kim, Na-eun Oh, Hayeon Lee, Seoyoung Park, Dong Keon Yon, Wu Seong Kang, Jinseok Lee Scientific Reports.2025;[Epub] CrossRef - The meaning and principles of damage control surgery
Gil Jae Lee Journal of the Korean Medical Association.2024; 67(12): 732. CrossRef - An Artificial Intelligence Model for Predicting Trauma Mortality Among Emergency Department Patients in South Korea: Retrospective Cohort Study
Seungseok Lee, Wu Seong Kang, Do Wan Kim, Sang Hyun Seo, Joongsuck Kim, Soon Tak Jeong, Dong Keon Yon, Jinseok Lee Journal of Medical Internet Research.2023; 25: e49283. CrossRef - Nonselective versus Selective Angioembolization for Trauma Patients with Pelvic Injuries Accompanied by Hemorrhage: A Meta-Analysis
Hyunseok Jang, Soon Tak Jeong, Yun Chul Park, Wu Seong Kang Medicina.2023; 59(8): 1492. CrossRef
- Rare Imaging of Fat Embolism Seen on Computed Tomography in the Common Iliac Vein after Polytrauma
-
Hojun Lee, Jonghwan Moon, Junsik Kwon, John Cook-Jong Lee
-
J Trauma Inj. 2018;31(2):103-106. Published online August 31, 2018
-
DOI: https://doi.org/10.20408/jti.2018.31.2.103
-
-
6,189
View
-
75
Download
-
1
Citations
-
Abstract
PDF
Fat embolism refers to the presence of fat droplets within the peripheral and lung microcirculation with or without clinical sequelae. However, early diagnosis of fat embolism is very difficult because the embolism usually does not show at the computed tomography as a large fat complex within vessels. Forty-eight-year-old male with pedestrian traffic accident ransferred from a local hospital by helicopter to the regional trauma center by two flight surgeons on board. At the rendezvous point, he had suffered with dyspnea without any airway obstruction sign with 90% of oxygen saturation from pulse oximetry with giving 15 L of oxygen by a reserve bag mask. The patient was intubated at the rendezvous point. The secondary survey of the patient revealed multiple pelvic bone fracture with sacrum fracture, right femur shaft fracture and right tibia head fracture. Abdominal computed tomography was performed in 191 minutes after the injury and fat embolism with Hounsfield unit of ?86 in his right common iliac vein was identified. Here is a very rare case that mass of fat embolism was shown within common iliac vein detected in computed tomography. Early detection of the fat embolus and early stabilization of the fractures are essential to the prevention of sequelae such as cerebral fat embolism.
-
Summary
-
Citations
Citations to this article as recorded by 
- Fat embolism in the popliteal vein detected on CT: Case report and review of the literature
Tucker Burr, Hamza Chaudhry, Cheryl Zhang, Vasilios Vasilopoulos, Emad Allam Radiology Case Reports.2020; 15(11): 2308. CrossRef
- Splenic Autotransplantation after Blunt Spleen Injury in Children
-
Hojun Lee, Byung Hee Kang, Junsik Kwon, John Cook-Jong Lee
-
J Trauma Inj. 2018;31(2):87-90. Published online August 31, 2018
-
DOI: https://doi.org/10.20408/jti.2018.31.2.87
-
-
5,502
View
-
99
Download
-
1
Citations
-
Abstract
PDF
Non-operative management has been preferred in blunt spleen injury. Moreover children are more susceptible to post-splenectomy infection, spleen should be preserved if possible. However, splenectomy is inevitable to patients with severe splenic injury. Therefore splenic autotransplantation could be the last chance for preserving splenic function in these patients although efficacy has not proven. Here we reported four cases of children who were underwent splenic autotransplantation successfully after blunt trauma.
-
Summary
-
Citations
Citations to this article as recorded by 
- Stumpfes Bauchtrauma bei Kindern und Jugendlichen: Behandlungskonzepte in der Akutphase
M. C. Schunn, J. Schäfer, F. Neunhoeffer, J. Lieber, J. Fuchs Die Chirurgie.2023; 94(7): 651. CrossRef
|